HCID 67206316, compound → HCID 21083669, compound

HRID 548404Notes

Reaction equation

HRID 548404 reaction equation
[C:1]1([CH2:7][C:8]([C:10]2[CH:11]=[C:12]3[C:17](=[CH:18][CH:19]=2)[NH:16][C:15](=[O:20])[C:14]([C:21]2[S:22][CH:23]=[CH:24][CH:25]=2)=[N:13]3)=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>[H][H].[Pd].C(O)(=O)C>[CH2:8]([C:10]1[CH:11]=[C:12]2[C:17](=[CH:18][CH:19]=1)[NH:16][C:15](=[O:20])[C:14]([C:21]1[S:22][CH:23]=[CH:24][CH:25]=1)=[N:13]2)[CH2:7][C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 1

HCID 67206316HCID 67206316, compound

Product 1

HCID 21083669HCID 21083669, compound

Reagents, catalysts & solvents 2

HCID 178506449HCID 178506449, compoundCatalystHCID 176Acetic AcidSolvent

Procedure

The quinoxalin-2-one of the present example is prepared with 6-Phenylacetyl-3-thiophen-2-yl-1H-quinoxalin-2-one from Example 46 via treatment with H2/Pd—C in the presence of acetic acid to form the 6-phenethyl compound.

Sources & evidence

ORD record
ord-520e807150504228b7c5d4ecf88ab93a
Source dataset
uspto-grants-2011_05
Patent number
USRE042375E1

Reaction notes

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