4-Chloro-3-fluorophenol → HCID 178447736, compound

HRID 54876Notes

Reaction equation

HRID 54876 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][C:3]=1[F:9].[C:10]1([Si:16]2(CCCCC)[CH2:21][CH2:20][CH:19]([C:22]3[CH:30]=[CH:29][C:25]([C:26](O)=[O:27])=[CH:24][CH:23]=3)[CH2:18][CH2:17]2)C=[CH:14][CH:13]=[CH:12][CH:11]=1>>[CH2:10]([Si@H:16]1[CH2:17][CH2:18][C@H:19]([C:22]2[CH:30]=[CH:29][C:25]([C:26]([O:8][C:5]3[CH:6]=[CH:7][C:2]([Cl:1])=[C:3]([F:9])[CH:4]=3)=[O:27])=[CH:24][CH:23]=2)[CH2:20][CH2:21]1)[CH2:11][CH2:12][CH2:13][CH3:14]

Participants

3

Reactant 2

HCID 27245234-Chloro-3-fluorophenolHCID 199567094-(4-Phenyl-4-n-pentyl-4-silacyclohexyl)benzoic acid

Product 1

HCID 178447736HCID 178447736, compound

Procedure

The general procedure of Example 3 was repeated using 4-chloro-3-fluorophenol and 4-(4-phenyl-4-n-pentyl-4-silacyclohexyl)benzoic acid, thereby obtaining the intended product.

Workup

  1. customobtaining the intended product

Sources & evidence

ORD record
ord-d883d5840f294ad6b71691504f19d907
Source dataset
uspto-grants-1997_04
Patent number
US05624601

Reaction notes

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