Methanol → HCID 58659264, compound

Participants

Reaction Steps

To a suspension of 9.25 g (31.96 mmol) of methyl 2-methoxy-6-(4-methyl benzylthio)pyridine-3-carboxylate in 80 mL of methanol was added 38.36 mL (38.36 mmol) of 1N-sodium hydroxide aqueous solution, and the mixture was refluxed for 1 hour. After the reaction mixture was cooled to the room temperature, the solvent was removed under reduced pressure and the residue was diluted with water. Then 2N-HCl was added to the solution and the resultant precipitate was collected to obtain 8.92 g (quantitative) of the title compound.

Provenance & Evidence