HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Hydroxyethyl)piperazine → HCID 25109091, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Hydroxyethyl)piperazine | HCID 7677 | — |
| Reactant | Phenyl 6-(2-fluoro-4-iodophenylamino)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate | HCID 59259226 | — |
| Product | HCID 25109091 | HCID 25109091 | — |
Reaction Steps
Example 44 was synthesized following a similar procedure described in the synthesis of Example 5 by reaction of compound 2A and 2-(piperazin-1-yl)ethanol. 1H NMR (400 MHz, CDCl3) δ 7.55 (m, 2H) 6.95 (t, J=8.0 Hz, 1H) 4.17 (br, 1H) 3.86 (br, 3H) 3.54 (br, 5H) 3.33 (br, 1H) 3.28 (br, 5H) 3.10 (br, 2H) 2.37 (br, 1H). [M+H] calc'd for C19H23FIN5O4, 532. found, 532.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07943626B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-9977668352b74f579d671ff6ec12bbdd |
| Source note | uspto-grants-2011_05 |