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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 548831Generated: October 30, 2026

Methyl malonyl chloride → HCID 67157102, compound

https://huagongshe.com/reaction/548831

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl malonyl chlorideHCID 123460—
Reactant6-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-pyridazin-3-ylamineHCID 42629771—
ProductHCID 67157102HCID 6715710232%

Reaction Steps

As described for example 18, 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-pyridazin-3-ylamine (200 mg, 0.7 mmol) was converted, using chlorocarbonyl-acetic acid methyl ester instead of methoxyacetyl chloride, to the title compound (88 mg, 32%) which was obtained as a white solid. MS: m/e=383.3 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07943619B2
Source datasetuspto-grants-2011_05
ORD IDord-3cafbba5e0e645d4a479cdbc119abb65
Source noteuspto-grants-2011_05