反应详情

As described for example 116e, 6-{[3-(3-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethyl]-amino}-pyridazine-3-carboxylic acid ethyl ester (107 mg, 0.3 mmol) was converted, using aminomethylcyclopropane instead of cyclopropylamine, to the title compound (72 mg, 63%) which was obtained as a white solid. MS: m/e=382.5 [M+H]+.