HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Pyridin-2-yl-isoxazole-4-carboxylic acid → (3-Pyridin-2-yl-isoxazol-4-yl)-methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Pyridin-2-yl-isoxazole-4-carboxylic acid | HCID 66643528 | — |
| Reactant | 5-Methyl-3-pyrimidin-4-yl-isoxazole-4-carboxylic acid | HCID 67157819 | — |
| Product | (3-Pyridin-2-yl-isoxazol-4-yl)-methanol | HCID 66643571 | 76.1% |
Reaction Steps
As described for example 114g, 3-pyridin-2-yl-isoxazole-4-carboxylic acid (39.0 g, 200 mmol) was converted, instead of 5-methyl-3-pyrimidin-4-yl-isoxazole-4-carboxylic acid, to the title compound (26.8 g, 76%) which was obtained as a white solid. MS: m/e=177.2 [M]−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07943619B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-a0952425a61b42a59fa6f5f438c1e4b3 |
| Source note | uspto-grants-2011_05 |