Fumaric Acid → HCID 67158127, compound

HRID 548944Notes

Reaction equation

HRID 548944 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][C:11]2([CH2:18][CH2:17][N:16]([C:19]3[CH:24]=[CH:23][C:22]([F:25])=[C:21]([Cl:26])[CH:20]=3)[CH2:15][CH2:14]2)[CH2:10][CH2:9]1)=O)(C)(C)C.[C:27]([OH:34])(=[O:33])/[CH:28]=[CH:29]/[C:30]([OH:32])=[O:31]>>[C:27]([OH:34])(=[O:33])/[CH:28]=[CH:29]/[C:30]([OH:32])=[O:31].[Cl:26][C:21]1[CH:20]=[C:19]([N:16]2[CH2:15][CH2:14][C:11]3([CH2:12][CH2:13][NH:8][CH2:9][CH2:10]3)[CH2:18][CH2:17]2)[CH:24]=[CH:23][C:22]=1[F:25]

Participants

3

Reactant 2

HCID 444972Fumaric AcidHCID 67158453HCID 67158453, compound

Product 1

HCID 67158127HCID 67158127, compound

Procedure

Was prepared according to method C from 9-(3-chloro-4-fluoro-phenyl)-3,9-diaza-spiro[5.5]undecane-3-carboxylic acid tert-butyl ester as the fumaric acid salt. Mp. 201.4-202.2° C.

Workup

  1. customWas prepared

Sources & evidence

ORD record
ord-9c141e3ff4784cf7a1cb8bb3c4623632
Source dataset
uspto-grants-2011_05
Patent number
US07943630B2

Reaction notes

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