4-Nitrobenzenesulfonamide → (RS)-S-Methyl-S-(4-nitrophenyl)-N-[(4-nitrophenyl)sulphonyl]sulphimide

Participants

Reaction Steps

879 mg (2.73 mmol) of iodosobenzene diacetate are added to a suspension of 300 mg (1.77 mmol) of 1-methylsulphanyl-4-nitrobenzene, 716 mg (3.55 mmol) of 4-nitrobenzenesulphonamide, 285 mg (7.10 mmol) of magnesium oxide and 78 mg (0.18 mmol) of rhodium(II) acetate dimer in 12 ml of dichloromethane at room temperature. The mixture is stirred for 24 h and then concentrated. The resulting residue is purified by chromatography (dichloromethane/ethanol 95:5). 484 mg (1.31 mmol; yield: 74%) of the product are obtained.

Provenance & Evidence