Methanesulfonamide → (RS)-S-(4-Nitrophenyl)-S-methyl-N-mesylsulphimide

Participants

Reaction Steps

879 mg (2.73 mmol) of iodosobenzene diacetate are added to a suspension of 300 mg (1.77 mmol) of 1-methylsulphanyl-4-nitrobenzene, 337 mg (3.55 mmol) of methanesulphonamide, 285 mg (7.10 mmol) of magnesium oxide and 78 mg (0.18 mmol) of rhodium(II) acetate dimer in 12 ml of dichloromethane at room temperature. The mixture is stirred for 24 h and then concentrated. The resulting residue is purified by chromatography (dichloromethane/ethanol 95:5). 133 mg (0.51 mmol; yield: 29%) of the product are obtained.

Provenance & Evidence