Bromobenzene → HCID 54718732, compound

Participants

Reaction Steps

214 mg of ethyl 1,6-dimethyl-4-hydroxy-2-oxo-1,2-dihydropyridine-3-carboxylate and 101 mg of 2-amino-5-methylpyridine were added to 2.5 ml of bromobenzene and the mixture was stirred for 6.5 hours under heat refluxing condition. The reaction mixture was cooled to room temperature, and t-butyl methyl ether and n-hexane were added to the mixture. The resulting solid was collected by filtration, washed with t-butyl methyl ether and n-hexane, and dried to obtain N-(5-methyl-2-pyridyl)-1,6-dimethyl-4-hydroxy-2-oxo-1,2-dihydropyridine-3-carboxamide

Provenance & Evidence