Ammonium Hydroxide → HCID 67157027, compound

Participants

Reaction Steps

A solution of 6-benzenesulfonyl-quinoline 1-oxid (135 mg, 0.47 mmol) in POCl3 (4 mL) was heated at 90° C. for 2 h after which the solution was poured on ice, ammonium hydroxide was added and extraction with DCM. The organic phase was dried (NaSO4), the volatiles were evaporated and the residue was purified by column chromatography (SiO2, ethyl acetate:petroleum ether, 1:1) to yield a white solid (39 mg, 27%). MS m/z: 305 [M+H+].

Provenance & Evidence