HRID549283

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COC(=O)[C@H]1[C@H]2C[C@@H]3c4[nH]c5cc(OC)ccc5c4CCN3C[C@H]2C[C@@H](OC(=O)c2cc(OC)c(OC)c(OC)c2)[C@@H]1OC

HCID5770

Reserpine

C33H40N2O9

HCID12210218

thieno[3,2-b]pyridine

C7H5NS

结构：CC(C)c1ccc(NS(=O)(=O)c2cc3c(Cl)nccc3s2)cc1

HCID87290241

未命名化合物

PRODUCTS

生成物

结构：CC(C)c1ccc(NS(=O)(=O)c2cc3c(N4CCNCC4)nccc3s2)cc1.Cl

HCID10343880

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6342

Acetonitrile

C2H3N

2 次

PROCEDURE

实验过程

4-Chloro-thieno[3,2-c]pyridine-2-sulfonic acid (4-isopropyl-phenyl)-amide (0.201 mmol, 1 equiv.) was used as the thienopyridine in Method H-L. Yield: 6.9 mg HPLC: tR=3.255 (System: 5% to 50% ACN in 3 min, C8), Purity: 95%, LC/MS: tR=1.255 (System: 30% to 60% ACN in 1.5 min, Hypersil BDS), Purity: 98%. MS: 417 (M+1). 1H NMR (270 MHz, CH3OH-d4) δ ppm 1.18 (d, J=6.86 Hz, 6H) 2.83 (m, 2H) 3.52 (m, 4H) 4.00 (m, 4H) 7.14 (m, 3H) 7.75 (d, J=6.60 Hz, 1H) 8.02 (m, 1H).