HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Cyanobenzenesulfonyl chloride → 4-(4-Piperazin-1-yl-pyrrolo[3,2-c]pyridine-1-sulfonyl)-benzonitrile Hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Cyanobenzenesulfonyl chloride | HCID 39497 | — |
| Reactant | 1-Piperazinecarboxylic acid,4-(1h-pyrrolo[3,2-c]pyridin-4-yl)-,1,1-dimethylethyl ester | HCID 67156709 | — |
| Product | 4-(4-Piperazin-1-yl-pyrrolo[3,2-c]pyridine-1-sulfonyl)-benzonitrile Hydrochloride | HCID 67156826 | — |
Reaction Steps
4-Cyanobenzenesulfonyl chloride (26.0 mg) was added to tert-butyl 4-(1H-pyrrolo[3,2-c]pyridin-4-yl)piperazine-1-carboxylate the title compound (9.1 mg). LC/MS RT: 1.150 (System 10 till 40% MeCN over 1.5 min, ACE C8), Purity. 93%. MS: 369 (M+1) 1HNMR (CD3OD) δ ppm 3.50 (m, 4H) 4.08 (m, 4H) 7.29 (d, J=3.71 Hz, 2H) 7.98 (m, 4H) 8.29 (d, J=8.66 Hz, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07943639B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-b47f263b2fda4480b20c78e82443c94d |
| Source note | uspto-grants-2011_05 |