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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 549311생성일: 2026년 10월 25일

4,5-Dichlorothiophene-2-sulfonyl chloride → 1-(4,5-Dichloro-thiophene-2-sulfonyl)-4-piperazin-1-yl-1H-pyrrolo[3,2-c]pyridine Hydrochloride

https://huagongshe.com/reaction/549311

반응식

참여 물질

역할이름HCID투입량
반응물4,5-Dichlorothiophene-2-sulfonyl chlorideHCID 518622—
반응물1-Piperazinecarboxylic acid,4-(1h-pyrrolo[3,2-c]pyridin-4-yl)-,1,1-dimethylethyl esterHCID 67156709—
생성물1-(4,5-Dichloro-thiophene-2-sulfonyl)-4-piperazin-1-yl-1H-pyrrolo[3,2-c]pyridine HydrochlorideHCID 67156653—

반응 단계

4,5-Dichloro-thiophene-2-sulfonyl chloride (32.4 mg) was added to tert-butyl 4-(1H-pyrrolo[3,2-c]pyridin-4-yl)piperazine-1-carboxylate the title compound (0.3 mg). LC/MS RT: 1.119 (System 10 till 40% MeCN over 1.5 min, ACE C8), Purity. 92%. MS: 418 (M+1).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07943639B2
출처 데이터셋uspto-grants-2011_05
ORD IDord-db581d2a579941038d561eb7f9c67cbb
출처 메모uspto-grants-2011_05