HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dicyclohexylcarbodiimide → (RS)2-(5-Pyridin-2-yl-[1,3,4]oxadiazol-2-ylmethyl)-piperidine-1-carboxylic acid tert butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | 1-Boc-2-Piperidineacetic Acid | HCID 5058536 | — |
| Reactant | HCID 178420173 | HCID 178420173 | — |
| Product | (RS)2-(5-Pyridin-2-yl-[1,3,4]oxadiazol-2-ylmethyl)-piperidine-1-carboxylic acid tert butyl ester | HCID 86628999 | 59.5% |
Reaction Steps
The title compound (1.39 g) was prepared from 2-carboxymethyl-piperidine-1-carboxylic acid tert butyl ester (1.65 g), 5-(pyridin-2-yl)tetrazole (1.0 g) and dicyclohexylcarbodiimide (1.43 g) according to the method of description 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07943645B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-78f0def5cbbd44c0b0d8e11dc36db304 |
| Source note | uspto-grants-2011_05 |