HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl piperidin-2-ylacetate → (1-{1-[5-(4-Fluoro-phenyl)-2-methyl-thiazol-4-yl]-methanoyl}-piperidin-2-yl)-acetic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl piperidin-2-ylacetate | HCID 5214606 | — |
| Reactant | 5-(4-Fluorophenyl)-2-methyl-1,3-thiazole-4-carboxylic acid | HCID 22324125 | — |
| Product | (1-{1-[5-(4-Fluoro-phenyl)-2-methyl-thiazol-4-yl]-methanoyl}-piperidin-2-yl)-acetic acid methyl ester | HCID 66968203 | 60.2% |
Reaction Steps
The title compound (2.1 g) was prepared from piperidin-2-yl-acetic acid methyl ester (3.4 g) and 2-methyl-5-(4-fluorophenyl)-thiazole-4-carboxylic acid (2.20 g) according to the method of description 20.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07943645B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-f0c35177fa2b4ce7b9687aa1a34dd777 |
| Source note | uspto-grants-2011_05 |