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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 549336Generated: October 25, 2026

Phenacylamine → (RS)-2-{[2-phenyl-2-oxo-ethylcarbamoyl]-methyl}-piperidine-1-carboxylic acid tert butyl ester

https://huagongshe.com/reaction/549336

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenacylamineHCID 11952—
Reactant1-Boc-2-Piperidineacetic AcidHCID 5058536—
Product(RS)-2-{[2-phenyl-2-oxo-ethylcarbamoyl]-methyl}-piperidine-1-carboxylic acid tert butyl esterHCID 8662900785%

Reaction Steps

The title compound (0.63 g) was prepared from 2-carboxymethyl-piperidine-1-carboxylic acid tert butyl ester (0.50 g) and 2-amino-1-phenylethanone (0.35 g) according to the method of description 54.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07943645B2
Source datasetuspto-grants-2011_05
ORD IDord-64fc7dbea9a34895982c9c852d289ad0
Source noteuspto-grants-2011_05