HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(2-Amino-benzoylamino)-thieno[2,3-c]pyrazole-1,5-dicarboxylic Acid 5-tert-butyl Ester 1-ethyl Ester → HCID 178450635, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(2-Amino-benzoylamino)-thieno[2,3-c]pyrazole-1,5-dicarboxylic Acid 5-tert-butyl Ester 1-ethyl Ester | HCID 57737268 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178450635 | HCID 178450635 | 91.4% |
Reaction Steps
30 mg of 3-(2-Amino-benzoylamino)-thieno[2,3-c]pyrazole-1,5-dicarboxylic acid 5-tert-butyl ester 1-ethyl ester (0.058 mmol) were treated with a 10% solution of TEA and methanol (8 mL) at room temperature for 3 hours. The solvent was removed under vacuum and the residue was purified by flash chromatography (eluant dichloromethane/methanol 99/1) yielding 19 mg (91%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07943654B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-8b9f0a07248640dcbee6bbce8cee03de |
| Source note | uspto-grants-2011_05 |