tert-Butyl 2-bromo-2-methylpropionate → HCID 131727544, compound

HRID 549469Notes

Reaction equation

HRID 549469 reaction equation
[CH2:1]([C:8]1[CH:13]=[CH:12][C:11]([C:14](=[O:36])[CH:15]=[CH:16][CH:17]2[C:22]([CH3:24])([CH3:23])[C:21]([CH3:25])=[C:20]([C:26]([O:28]C(C)(C)C)=[O:27])[C:19]([CH3:33])=[C:18]2[O:34][CH3:35])=[CH:10][CH:9]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7].BrC(C)(C)C(OC(C)(C)C)=O>>[CH2:1]([C:8]1[CH:9]=[CH:10][C:11]([C:14](=[O:36])[CH:15]=[CH:16][CH:17]2[C:22]([CH3:23])([CH3:24])[C:21]([CH3:25])=[C:20]([C:26]([OH:28])=[O:27])[C:19]([CH3:33])=[C:18]2[O:34][CH3:35])=[CH:12][CH:13]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7]

Participants

3

Reactant 2

HCID 90290tert-Butyl 2-bromo-2-methylpropionateHCID 131727545HCID 131727545, compound2×

Product 1

HCID 131727544HCID 131727544, compound

Procedure

This compound was synthesized from 1-[4-heptylphenyl]-3-[3,5-dimethyl-4-tertbutyloxycarbonyldimethylmethyloxyphenyl]prop-2-en-1-one (compound 38) and tertbutyl bromoisobutyrate according to general method 4 described earlier.

Sources & evidence

ORD record
ord-5848ecc26b0a4c059621b2d839a39b3d
Source dataset
uspto-grants-2011_05
Patent number
US07943661B2

Reaction notes

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