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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 549516Generated: October 31, 2026

D-Serine → N-{[3-(4-{[4-[5-Fluoro-2-(methyloxy)phenyl]-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl]amino}-6-methyl-1H-indazol-1-yl)phenyl]carbonyl}-D-serine

https://huagongshe.com/reaction/549516

Reaction equation

Participants

RoleNameHCIDCharge
ReactantD-SerineHCID 71077—
Reactant3-(4-{[4-[5-fluoro-2-(methyloxy)phenyl]-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl]amino}-6-methyl-1H-indazol-1-yl)benzoic acidHCID 25180783—
ProductN-{[3-(4-{[4-[5-Fluoro-2-(methyloxy)phenyl]-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl]amino}-6-methyl-1H-indazol-1-yl)phenyl]carbonyl}-D-serineHCID 57672647—

Reaction Steps

Prepared similarly to Intermediate 4 from 3-(4-{[4-[5-fluoro-2-(methyloxy)phenyl]-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl]amino}-6-methyl-1H-indazol-1-yl)benzoic acid and D-serine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07943651B2
Source datasetuspto-grants-2011_05
ORD IDord-8d9f6dc348794876a5e9960c926cb12f
Source noteuspto-grants-2011_05