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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 549529Generated: October 27, 2026

(S)-2-aminopropanamide hydrochloride → HCID 24782160, compound

https://huagongshe.com/reaction/549529

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-2-aminopropanamide hydrochlorideHCID 2775816—
Reactant3-(4-{[4-[5-fluoro-2-(methyloxy)phenyl]-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl]amino}-6-methyl-1H-indazol-1-yl)benzoic acidHCID 25180783—
ProductHCID 24782160HCID 24782160—

Reaction Steps

Prepared similarly to Example 1 from 3-(4-{[4-[5-fluoro-2-(methyloxy)phenyl]-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl]amino}-6-methyl-1H-indazol-1-yl)benzoic acid and L-alaninamide hydrochloride with System A used for purification by mass directed autopreparation.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07943651B2
Source datasetuspto-grants-2011_05
ORD IDord-7d2870906451406eac913e34bc9683f0
Source noteuspto-grants-2011_05