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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 549530Generated: October 30, 2026

2-Amino-2-methylpropanamide → N-(2-Amino-1,1-dimethyl-2-oxoethyl)-3-(4-{[4-[5-fluoro-2-(methyloxy)phenyl]-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl]amino}-6-methyl-1H-indazol-1-yl)benzamide

https://huagongshe.com/reaction/549530

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-2-methylpropanamideHCID 6453783—
Reactant3-(4-{[4-[5-fluoro-2-(methyloxy)phenyl]-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl]amino}-6-methyl-1H-indazol-1-yl)benzoic acidHCID 25180783—
ProductN-(2-Amino-1,1-dimethyl-2-oxoethyl)-3-(4-{[4-[5-fluoro-2-(methyloxy)phenyl]-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl]amino}-6-methyl-1H-indazol-1-yl)benzamideHCID 24782161—

Reaction Steps

Prepared similarly to Example 1 from 3-(4-{[4-[5-fluoro-2-(methyloxy)phenyl]-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl]amino}-6-methyl-1H-indazol-1-yl)benzoic acid and 2-methylalaninamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07943651B2
Source datasetuspto-grants-2011_05
ORD IDord-489dc7c6b76c4348a92db8df92b8e92f
Source noteuspto-grants-2011_05