Oxalic Acid → HCID 86623396, compound

Participants

Reaction Conditions

Reaction Steps

Almotriptan crude (10 gms, purity 92.5%) is dissolved in Ethanol (60 ml) at room temperature. Reaction mass is stirred for 15 min for the complete dissolution. Oxalic Acid solution (4.0 gms in 15 ml Ethanol) is added to the above solution over 30 min at room temperature. Reaction mass temperature is raised to reflux and maintained for about 6 hrs. Slowly cooled the reaction mass to 0° C. and maintained for about 1 hr at 0±3° C. The precipitated material is filtered and washed with 15 ml of Ethanol.

Provenance & Evidence