3-Bromobenzoic acid → 3-Bromo-1-(5-n-propyl-2-thienylmethyl)benzene

HRID 549986Notes

Reaction equation

HRID 549986 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][CH:10]=1)[C:5](O)=O.[CH2:11]([C:14]1[S:15][CH:16]=[CH:17][CH:18]=1)[CH2:12][CH3:13]>>[Br:1][C:2]1[CH:3]=[C:4]([CH2:5][C:16]2[S:15][C:14]([CH2:11][CH2:12][CH3:13])=[CH:18][CH:17]=2)[CH:8]=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 114563-Bromobenzoic acidHCID 737712-Propylthiophene

Product 1

HCID 666082763-Bromo-1-(5-n-propyl-2-thienylmethyl)benzene

Procedure

3-Bromobenzoic acid and 2-n-propylthiophene were used and treated in a manner similar to Reference Example 5 to give the target compound.

Workup

  1. additiontreated in a manner similar to Reference Example 5
  2. customto give the target compound

Sources & evidence

ORD record
ord-d9f33f617d12479f9a410c5dcdb4472e
Source dataset
uspto-grants-2011_05
Patent number
US07943788B2

Reaction notes

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