2-Ethylthiophene → 3-Bromo-1-(5-ethyl-2-thienylmethyl)-4-methoxybenzene

HRID 549987Notes

Reaction equation

HRID 549987 reaction equation
[CH2:1]([C:3]1[S:4][CH:5]=[CH:6][CH:7]=1)[CH3:2].[Br:8][C:9]1[CH:10]=[C:11]([CH:14]=[CH:15][C:16]=1[O:17][CH3:18])[CH:12]=O>>[Br:8][C:9]1[CH:10]=[C:11]([CH2:12][C:5]2[S:4][C:3]([CH2:1][CH3:2])=[CH:7][CH:6]=2)[CH:14]=[CH:15][C:16]=1[O:17][CH3:18]

Participants

3

Reactant 2

HCID 133882-EthylthiopheneHCID 986623-Bromo-4-methoxybenzaldehyde

Product 1

HCID 666082333-Bromo-1-(5-ethyl-2-thienylmethyl)-4-methoxybenzene

Procedure

2-Ethylthiophene and 3-bromo-4-methoxybenzaldehyde were used and treated in a manner similar to Reference Example 7 to give the target compound.

Workup

  1. additiontreated in a manner similar to Reference Example 7
  2. customto give the target compound

Sources & evidence

ORD record
ord-a6a9b7429b2147daae0c977790fafbca
Source dataset
uspto-grants-2011_05
Patent number
US07943788B2

Reaction notes

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