3-Ethylthiophene → 3-Bromo-1-(4-ethyl-2-thienylmethyl)benzene

HRID 549989Notes

Reaction equation

HRID 549989 reaction equation
[CH2:1]([C:3]1[CH:7]=[CH:6][S:5][CH:4]=1)[CH3:2].[Br:8][C:9]1[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=1)[CH:12]=O>>[Br:8][C:9]1[CH:10]=[C:11]([CH2:12][C:6]2[S:5][CH:4]=[C:3]([CH2:1][CH3:2])[CH:7]=2)[CH:14]=[CH:15][CH:16]=1

Participants

3

Reactant 2

HCID 745303-EthylthiopheneHCID 765833-Bromobenzaldehyde

Product 1

HCID 666084413-Bromo-1-(4-ethyl-2-thienylmethyl)benzene

Procedure

3-Ethylthiophene and 3-bromobenzaldehyde were used and treated in a manner similar to Reference Example 9 to give the target compound. APCI-Mass m/Z 281/283 (M+H).

Workup

  1. additiontreated in a manner similar to Reference Example 9
  2. customto give the target compound

Sources & evidence

ORD record
ord-c51dc8f7eda449f9b73a027c2ed2326b
Source dataset
uspto-grants-2011_05
Patent number
US07943788B2

Reaction notes

Loading…