5-Bromo-2-fluorobenzaldehyde → HCID 66608986, compound

HRID 550010Notes

Reaction equation

HRID 550010 reaction equation
[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[C:10]1[S:11][CH:12]=[CH:13][CH:14]=1)[CH3:2].[Br:15][C:16]1[CH:17]=[CH:18][C:19]([F:24])=[C:20]([CH:23]=1)[CH:21]=O>>[Br:15][C:16]1[CH:17]=[CH:18][C:19]([F:24])=[C:20]([CH2:21][C:12]2[S:11][C:10]([C:5]3[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=3[O:3][CH2:1][CH3:2])=[CH:14][CH:13]=2)[CH:23]=1

Participants

3

Reactant 2

HCID 7363275-Bromo-2-fluorobenzaldehydeHCID 20514143HCID 20514143, compound

Product 1

HCID 66608986HCID 66608986, compound

Procedure

2-(2-Ethoxyphenyl)thiophene obtained in Reference Example 70-(1) and 5-bromo-2-fluorobenzaldehyde were treated in a manner similar to Reference Example 9 to give the target compound. APCI-Mass m/Z 391/393 (M+H).

Workup

  1. customto give the target compound

Sources & evidence

ORD record
ord-e42ef590b2d84bb890ec0b3f710a6fc6
Source dataset
uspto-grants-2011_05
Patent number
US07943788B2

Reaction notes

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