HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22923383, compound → 3-[1-(6,7-Dimethoxy-4-quinazolinyl)-4-piperidinyl]-1,2,3,4-tetrahydro-1,8-dimethyl-2,4-dioxoquinazoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22923383 | HCID 22923383 | — |
| Reactant | 3-[1-(6,7-Dimethoxy-4-quinazolinyl)-4-piperidinyl]-1,2,3,4-tetrahydro-6-nitro-2,4-dioxoquinazoline | HCID 22923399 | — |
| Product | 3-[1-(6,7-Dimethoxy-4-quinazolinyl)-4-piperidinyl]-1,2,3,4-tetrahydro-1,8-dimethyl-2,4-dioxoquinazoline | HCID 22923509 | 61% |
Reaction Steps
The procedure similar to that described in Example 1 was repeated, except that 300 mg (0.67 mmol) of 3-[1-(6,7-dimethoxy-4-quinazolinyl)-4-piperidinyl]-1,2,3,4-tetrahydro-8-methyl-2,4-dioxoquinazoline (Compound 101) obtained in Reference Example 12 was used in place of Compound 24. As a result, 185.2 mg (yield: 61%) of Compound 59 was obtained as white crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05624926 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-9dc901adbf3d4ed286fdca7b8cdb9fc5 |
| Source note | uspto-grants-1997_04 |