HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 4-[4-(Dimethylamino)phenyl]-1-methylpyridin-1-ium iodide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | N,N-dimethyl-4-(pyridin-4-yl)aniline | HCID 227783 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 4-[4-(Dimethylamino)phenyl]-1-methylpyridin-1-ium iodide | HCID 13227270 | — |
Reaction Steps
N,N-dimethyl-4-(pyridine-4-yl) aniline (0.15 g, 7.6 mmols) was dissolved in acetonitrile (50 ml) and methyl iodide (4 ml) was added. The mixture was heated at reflux for 4 hrs then cooled to ambient temperature. IDT307 (0.17 g, 5 mmols) crystallized upon standing and was removed via filtration. 1H NMR (DMSO-d6) δ 3.40 (s, 6H), 4.25 (s, 3H), 6.92 (d, 2H), 8.06 (d, 2H), 8.38 (d, 2H), 8.80 (d, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07947255B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-bee9dd0130944a38adeee03e9d76b33b |
| Source note | uspto-grants-2011_05 |