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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 550335Generated: October 29, 2026

D-Glucosamine → D-glucosamine 5-methyl-(6R,S)-tetrahydrofolate

https://huagongshe.com/reaction/550335

Reaction equation

Participants

RoleNameHCIDCharge
ReactantD-GlucosamineHCID 439213—
Reactant(6r,s)-5-Methyltetrahydrofolic acidHCID 135430866—
ProductD-glucosamine 5-methyl-(6R,S)-tetrahydrofolateHCID 136356796136.8%

Reaction Steps

4.60 g (10 mmol) of 5-methyl-(6R,S)-tetrahydrofolic acid were added portion-wise and completely dissolved in 30 ml of an aqueous solution of D-glucosamine (3.58 g, 20 mmol) stirred under nitrogen. The resulting solution (pH 6.53) was freeze-dried, obtaining 8.72 g of the title product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07947662B2
Source datasetuspto-grants-2011_05
ORD IDord-9a15fcda5573442494b4e362579beff5
Source noteuspto-grants-2011_05