HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 1-Piperidin-4-ylimidazolidine-2,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Tert-butyl 4-(2,4-dioxoimidazolidin-1-yl)piperidine-1-carboxylate | HCID 57428924 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1-Piperidin-4-ylimidazolidine-2,4-dione | HCID 57428923 | — |
Reaction Steps
Trifluoroacetic acid (0.300 mL) was added to a solution of tert-butyl 4-(2,4-dioxoimidazolidin-1-yl)piperidine-1-carboxylate (32 mg, 0.113 mmol) in dichloromethane (1 mL). After 4 h, the reaction was concentrated to give the title compound. MS: m/z=184.04 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07947678B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-ae3f143990dd48e28007e0ab919a8755 |
| Source note | uspto-grants-2011_05 |