Diethanolamine → 2,2'-({2-[(4-{[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]amino}-1H-pyrazolo[3,4-d]pyrimidin-3-yl)oxy]ethyl}imino)diethanol

Participants

Reaction Steps

The procedure described in Example 23 was repeated using 3-(2-chloroethoxy)-N-[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine and diethanolamine to give the title compound in 18% yield; NMR Spectrum: 2.66 (t, 4H), 2.98 (t, 2H), 3.44-3.48 (m, 4H), 4.35 (t, 2H), 4.43 (t, 2H), 5.28 (s, 2H), 7.23 (d, 1H), 7.37 (t, 1H), 7.57-7.60 (m, 2H), 7.87 (t, 1H), 7.94 (d, 1H), 8.29 (s, 1H), 8.44 (s, 1H), 8.59 (d, 1H); Mass Spectrum: 500 (MH+).

Provenance & Evidence