Potassium Iodide → HCID 11648063, compound

Participants

Reaction Steps

The procedure described in Example 23 was repeated (except that potassium iodide was not used) using 2-{[4-({3-fluoro-4-[(6-methylpyridin-3-yl)oxy]phenyl}amino)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]oxy}ethyl methanesulfonate and pyrrolidine to give the title compound in 54% yield; NMR Spectrum: 1.67 (s, 4H), 2.45 (s, 3H), 2.54 (hidden by DMSO, 4H), 2.89 (t, 2H), 4.45 (t, 2H), 7.23 (m, 3H), 7.53 (dd, 1H), 8.01 (dd, 1H), 8.24 (d, 1H), 8.36 (s, 1H), 8.70 (br s, 1H); Mass Spectrum: 450 (MH+).

Provenance & Evidence