Piperidin-4-ol → HCID 44455330, compound

Participants

Reaction Steps

The procedure described in Example 23 was repeated using 3-(2-chloroethoxy)-N-[3-methyl-4-(pyridin-2-ylmethoxy)phenyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine and 4-hydroxypiperidine to give the title compound in 39% yield; NMR Spectrum: 1.36 (d, 2H), 1.69 (d, 2H), 2.18 (t, 2H), 2.26 (s, 3H), 2.78 (m, 4H), 4.39 (t, 2H), 4.54 (d, 1H), 5.20 (s, 2H), 6.98 (d, 1H), 7.35 (t, 1H), 7.44 (m, 2H), 7.55 (d, 1H), 7.86 (t, 1H), 8.21 (s, 1H), 8.23 (s, 1H), 8.59 (d, 1H); Mass Spectrum: 476 (MH+).

Provenance & Evidence