(2-Methoxyethyl)(methyl)amine → HCID 67020785, compound

Participants

Reaction Steps

The procedure described in Example 23 was repeated using 3-(2-chloroethoxy)-N-{3-chloro-4-[(6-methylpyridin-3-yl)oxy]phenyl}-1H-pyrazolo[3,4-d]pyrimidin-4-amine (prepared as described in Example 16) and (2-methoxyethyl)methylamine to give the title compound in 52% yield; NMR Spectrum: 2.30 (s, 3H), 2.45 (s, 3H), 2.62 (t, 2H), 2.86 (t, 2H), 3.17 (s, 3H), 3.41 (t, 2H), 4.41 (t, 2H), 7.19 (d, 1H), 7.26 (br s, 2H), 7.72 (d, 1H), 8.14 (s, 1H), 8.21 (s, 1H), 8.36 (s, 1H), 8.62 (br s, 1H); Mass Spectrum: 484 (MH+).

Provenance & Evidence