2-Amino-5-fluoropyridine → HCID 67151995, compound

HRID 550589Notes

Reaction equation

HRID 550589 reaction equation
[C:1]([O:5][C:6]([N:8]([C:19]1[CH:20]=[N:21][CH:22]=[CH:23][CH:24]=1)[C:9]1[C:10]([C:16](O)=[O:17])=[N:11][C:12]([CH3:15])=[CH:13][N:14]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[NH2:25][C:26]1[CH:31]=[CH:30][C:29]([F:32])=[CH:28][N:27]=1>>[C:1]([O:5][C:6](=[O:7])[N:8]([C:9]1[C:10]([C:16](=[O:17])[NH:25][C:26]2[CH:31]=[CH:30][C:29]([F:32])=[CH:28][N:27]=2)=[N:11][C:12]([CH3:15])=[CH:13][N:14]=1)[C:19]1[CH:20]=[N:21][CH:22]=[CH:23][CH:24]=1)([CH3:3])([CH3:2])[CH3:4]

Participants

3

Reactant 2

HCID 27377012-Amino-5-fluoropyridineHCID 67151980HCID 67151980, compound

Product 1

HCID 67151995HCID 67151995, compound

Procedure

The title compound, MS: m/e=425.2 (M+H+), was prepared in accordance with the general method of example 8, step 3 from 3-(tert-butoxycarbonyl-pyridin-3-yl-amino)-6-methyl-pyrazine-2-carboxylic acid and 2-amino-5-fluoropyridine.

Sources & evidence

ORD record
ord-f96752e0bccf4a1d9235cacc4b284889
Source dataset
uspto-grants-2011_05
Patent number
US07947685B2

Reaction notes

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