HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloroaniline → 6-Methyl-3-(pyrimidin-5-ylamino)-pyrazine-2-carboxylic acid (3-chloro-phenyl)-amide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloroaniline | HCID 7932 | — |
| Reactant | 5-Bromopyrimidine | HCID 78344 | — |
| Reactant | Ethyl 3-amino-6-methylpyrazine-2-carboxylate | HCID 317738 | — |
| Product | 6-Methyl-3-(pyrimidin-5-ylamino)-pyrazine-2-carboxylic acid (3-chloro-phenyl)-amide hydrochloride | HCID 11996629 | — |
Reaction Steps
The title compound, MS: m/e=341.2 (M+H+), was prepared in accordance with the general method of example 10 from 3-amino-6-methyl-pyrazine-2-carboxylic acid ethyl ester (Example C), 5-bromopyrimidine and 3-chloroaniline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07947685B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-f7aa3b4b3b47400392af85f410427e24 |
| Source note | uspto-grants-2011_05 |