HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-4-methylthiazole → 6-Methyl-3-(pyrimidin-5-ylamino)-pyrazine-2-carboxylic acid (4-methyl-thiazol-2-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-4-methylthiazole | HCID 74143 | — |
| Reactant | 5-Bromopyrimidine | HCID 78344 | — |
| Reactant | Ethyl 3-amino-6-methylpyrazine-2-carboxylate | HCID 317738 | — |
| Product | 6-Methyl-3-(pyrimidin-5-ylamino)-pyrazine-2-carboxylic acid (4-methyl-thiazol-2-yl)-amide | HCID 11996469 | — |
Reaction Steps
The title compound, MS: m/e=328.3 (M+H+), was prepared in accordance with the general method of example 10 from 3-amino-6-methyl-pyrazine-2-carboxylic acid ethyl ester (Example C), 5-bromopyrimidine and 2-amino-4-methylthiazole
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07947685B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-25a1e54bc31f4689935abfafe3b429d5 |
| Source note | uspto-grants-2011_05 |