Dichloromethane → HCID 67202227, compound

Participants

Reaction Steps

To a solution of 3-amino-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-2,5-dicarboxylic acid 5-tert-butyl ester 2-ethyl ester (40 g, 128.9 mmol) in dichloromethane (1 L), 4 N HCl in dioxane (161 mL, 644.5 mmol) was added dropwise. The mixture was stirred at room temperature for 4 hours. The solid was filtered, washed with dichloromethane and diethylether. After drying in vacuo the title compound was obtained as white solid (36.2 g, 99%).

Provenance & Evidence