Aluminium lithium hydride → 2-(5-Methyl-2-thienyl)ethanamine

HRID 550618Notes

Reaction equation

HRID 550618 reaction equation
[CH3:1][C:2]1[S:3][C:4]([CH:7]=[CH:8][N+:9]([O-])=O)=[CH:5][CH:6]=1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[CH3:1][C:2]1[S:3][C:4]([CH2:7][CH2:8][NH2:9])=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 539158762-Methyl-5-(2-nitro-vinyl)-thiophene

Product 1

HCID 147881892-(5-Methyl-2-thienyl)ethanamineYield 85%

Procedure

In close analogy to the procedure described above, 2-Methyl-5-(2-nitro-vinyl)-thiophene is reacted with lithium aluminium hydride to provide the title compound.

Sources & evidence

ORD record
ord-c5da6e521ddf4902a741127f53999d34
Source dataset
uspto-grants-2011_05
Patent number
US07947689B2

Reaction notes

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