Phosphorus oxide (P4O10) → 2,3,4-Trimethyl-6,7-dihydrothieno[3,2-c]pyridine

HRID 550633Notes

Reaction equation

HRID 550633 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH2:8][CH2:9][NH:10][C:11](=O)[CH3:12])[S:5][C:6]=1[CH3:7].O=P12OP3(OP(OP(O3)(O1)=O)(=O)O2)=O>>[CH3:7][C:6]1[S:5][C:4]2[CH2:8][CH2:9][N:10]=[C:11]([CH3:12])[C:3]=2[C:2]=1[CH3:1]

Participants

3

Reactant 2

HCID 14812Phosphorus oxide (P4O10)HCID 59663060N-[2-(4,5-Dimethyl-thiophen-2-yl)-ethyl]-acetamide

Product 1

HCID 596630912,3,4-Trimethyl-6,7-dihydrothieno[3,2-c]pyridine

Procedure

In close analogy to the procedure described above, N-[2-(4,5-Dimethyl-thiophen-2-yl)-ethyl]-acetamide is reacted with phosphorus pentoxide to provide the title compound.

Sources & evidence

ORD record
ord-ce1fbe30385a419e90d91c25811c26b7
Source dataset
uspto-grants-2011_05
Patent number
US07947689B2

Reaction notes

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