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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 550635Generated: October 29, 2026

Phosphorus oxide (P4O10) → 4-methyl-6H,7H-thieno[3,2-c]pyridine

https://huagongshe.com/reaction/550635

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphorus oxide (P4O10)HCID 14812—
Reactant2,2,2-trifluoro-N-[2-(thiophen-2-yl)ethyl]acetamideHCID 57130484—
Product4-methyl-6H,7H-thieno[3,2-c]pyridineHCID 2182117725%

Reaction Steps

In close analogy to the procedure described above, 2,2,2-Trifluoro-N-(2-thiophen-2-yl-ethyl)-acetamide is reacted with phosphorus pentoxide to provide the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07947689B2
Source datasetuspto-grants-2011_05
ORD IDord-79f00a2c64a744b78dbec112e3f81361
Source noteuspto-grants-2011_05