HCID 24899497, compound → HCID 178421625, compound

HRID 550686Notes

Reaction equation

HRID 550686 reaction equation
[Br:1][C:2]1[CH:3]=[N:4][C:5]2[N:6]([N:8]=[C:9]([C:11]([N:13]3[CH2:18][CH2:17][C:16]4[NH:19][CH:20]=[CH:21][C:15]=4[CH:14]3[CH3:22])=[O:12])[CH:10]=2)[CH:7]=1.[NH:23]1[CH:27]=[N:26][N:25]=[N:24]1>>[Br:1][C:2]1[CH:3]=[N:4][C:5]2[N:6]([N:8]=[C:9]([C:11]([N:13]3[CH2:18][CH2:17][C:16]4[N:19]([C:27]5[NH:26][N:25]=[N:24][N:23]=5)[CH:20]=[CH:21][C:15]=4[CH:14]3[CH3:22])=[O:12])[CH:10]=2)[CH:7]=1

Participants

3

Reactant 2

HCID 24899497HCID 24899497, compoundHCID 178418441HCID 178418441, compound

Product 1

HCID 178421625HCID 178421625, compound

Procedure

(6-Bromo-pyrazolo[1,5-a]pyrimidin-2-yl)-(4-methyl-1,4,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-5-yl)-methanone is reacted with 1H tetrazole under Buchwald reaction conditions to provide the title compound.

Sources & evidence

ORD record
ord-df240cf77c5a470ea6bab480265ab1db
Source dataset
uspto-grants-2011_05
Patent number
US07947689B2

Reaction notes

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