HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-4-isothiocyanato-2-(trifluoromethyl)benzene → 1-[4-(4-Quinolylthio)phenyl]-3-(4-chloro-3-trifluoromethylphenyl)thiourea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-4-isothiocyanato-2-(trifluoromethyl)benzene | HCID 520026 | — |
| Reactant | 4-(4-Aminophenylthio)quinoline | HCID 18971653 | — |
| Product | 1-[4-(4-Quinolylthio)phenyl]-3-(4-chloro-3-trifluoromethylphenyl)thiourea | HCID 18971686 | 56% |
Reaction Steps
4-(4-aminophenylthio)quinoline (3.9 moles, 1.0 g) and 4-chloro-3-trifluoromethylphenylisothiocyanate (3.9 moles, 0.92 g) were reacted according to procedure A to yield of the title compound 1.06 g, 56%. Mass spec (FD) 490. Calculated for C23H15ClF3N3S2 : C, 56.38; H, 3.09, N, 8.58. Found: C, 56.60; H, 3.11; N, 8.42.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05624937 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-be5e0f6c98d84a9c9fc8f4d0c5dd3966 |
| Source note | uspto-grants-1997_04 |