6-Chloropyrazolo[1,5-A]pyrimidine-2-carboxylic acid → HCID 24896782, compound

HRID 550694Notes

Reaction equation

HRID 550694 reaction equation
[Cl:1][C:2]1[CH:3]=[N:4][C:5]2[N:6]([N:8]=[C:9]([C:11]([OH:13])=O)[CH:10]=2)[CH:7]=1.[Cl:14][C:15]1[S:24][C:18]2[CH:19]([CH3:23])[NH:20][CH2:21][CH2:22][C:17]=2[CH:16]=1>>[Cl:14][C:15]1[S:24][C:18]2[CH:19]([CH3:23])[N:20]([C:11]([C:9]3[CH:10]=[C:5]4[N:4]=[CH:3][C:2]([Cl:1])=[CH:7][N:6]4[N:8]=3)=[O:13])[CH2:21][CH2:22][C:17]=2[CH:16]=1

Participants

3

Reactant 2

HCID 336956786-Chloropyrazolo[1,5-A]pyrimidine-2-carboxylic acidHCID 67193996HCID 67193996, compound

Product 1

HCID 24896782HCID 24896782, compound

Procedure

In close analogy to the procedure described in Example 1, 6-chloro-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid is reacted with 2-chloro-7-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine to provide the title compound.

Sources & evidence

ORD record
ord-ffb00e06104b46d68e5f3b85ebad0e77
Source dataset
uspto-grants-2011_05
Patent number
US07947689B2

Reaction notes

Loading…