(1-Bromoethyl)benzene → HCID 11537374, compound

Participants

Reaction Steps

Following general procedure B2 and D1, 3-(2,4-Dimethoxy-benzyloxy)-1H-benzo[4,5]thieno[3,2-d]pyrimidine-2,4-dione was alkylated with (1-Bromoethyl)-benzene and subsequently deprotected to provide the title compound as a white solid. 1H NMR (d6-DMSO, 300 MHz) δ 2.16 (d, J=7 Hz, 3H); 6.49 (q, J=7 Hz, 1H); 7.30-7.65 (m, 6H); 7.73 (dd, J=8 Hz, 1H); 8.10 (d, J=8 Hz, 1H); 8.31 (d, J=8 Hz, 1H); 10.80 (br s, 1H); Retention time=2.70 min., m/z=339.0.

Provenance & Evidence