Benzyl Bromide → HCID 11653561, compound

Participants

Reaction Steps

Following general procedure B2 and D1, 3-(2,4-Dimethoxy-benzyloxy)-8-nitro-1H-benzo[4,5]thieno[3,2-d]pyrimidine-2,4-dione was alkylated with benzyl bromide and subsequently deprotected to provide the title compound as a light yellow solid. 1H NMR (d6-DMSO, 300 MHz) δ 5.77 (s, 2H); 7.24-7.40 (m, 5H), 8.29 (dd, J1=9 Hz, J2=2 Hz, 1H); 8.40 (d, J=9 Hz, 1H); 8.71 (d, J=2 Hz, 1H); Ret. time=2.56 min., m/z=368.0.

Provenance & Evidence