(2H-1,3-benzodioxol-5-yl)boronic acid → HCID 11560977, compound

Participants

Reaction Steps

1-(2-Bromo-benzyl)-3-hydroxy-1H-benzo[4,5]furo[3,2-d]pyrimidine-2,4-dione was treated with 3,4-methylenedioxyphenylboronic acid according to general procedure C to provide the title compound as a yellow solid. 1H NMR (d6-DMSO, 300 MHz) 5.61 (s, 2H); 6.05 (s, 2H); 6.98 (d, J=8 Hz, 1H); 7.10 (dd, J1=8 Hz, J2=2 Hz, 1H); 7.18-7.21 (m, 2H); 7.35 (dd, J=8 Hz, 2H); 7.49 (br d, J=8 Hz, 1H); 7.57-7.62 (m, 2H); 7.80 (d, J=8 Hz, 1H); 7.87 (d, J=8 Hz, 1H); Ret. time=2.95 min., m/z=429.0.

Provenance & Evidence