1-Chloro-4-isothiocyanato-2-(trifluoromethyl)benzene → HCID 18971664, compound

HRID 55088Notes

Reaction equation

HRID 55088 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]2[CH:18]=[CH:17][C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[N:10]=2)=[CH:4][CH:3]=1.[Cl:19][C:20]1[CH:25]=[CH:24][C:23]([N:26]=[C:27]=[S:28])=[CH:22][C:21]=1[C:29]([F:32])([F:31])[F:30]>>[N:10]1[C:11]2[C:16](=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:17]=[CH:18][C:9]=1[NH:8][C:5]1[CH:4]=[CH:3][C:2]([NH:1][C:27]([NH:26][C:23]2[CH:24]=[CH:25][C:20]([Cl:19])=[C:21]([C:29]([F:32])([F:30])[F:31])[CH:22]=2)=[S:28])=[CH:7][CH:6]=1

Participants

3

Reactant 2

HCID 5200261-Chloro-4-isothiocyanato-2-(trifluoromethyl)benzeneHCID 18971656HCID 18971656, compound

Product 1

HCID 18971664HCID 18971664, compoundYield 68%

Procedure

2-(4-aminophenylamino)quinoline (5.0 moles, 1.15 g) and 4-chloro-3-trifluoromethylphenylisothiocyanate (5.0 moles, 1.20 g) were reacted according to procedure C of to yield the title compound 1.60 g, 68%. Mass Spec (FD) 473. Calculated for C23H16C1F3N4S: C,; H,; N, Found: C,; H,; N,.

Sources & evidence

ORD record
ord-6ab81fbcca4749f5a3b132203b0abb14
Source dataset
uspto-grants-1997_04
Patent number
US05624937

Reaction notes

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